Molecular Docking and Molecular Dynamic Studies of Semi-Synthetic Piperidine Alkaloids as Acetylcholinesterase Inhibitors
نویسندگان
چکیده
Núcleo de Bioensaios, Biossíntese e Ecofisiologia de Produtos Naturais (NuBBE), Departamento de Química Orgânica, Instituto de Química, Universidade Estadual Paulista ‘Julio de Mesquita Filho’, CP 355, 14801-970 Araraquara-SP, Brazil Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, CP 68023, 21944-910 Rio de Janeiro-RJ, Brazil Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves 9500, CP 15005, 91500-970 Porto Alegre-RS, Brazil Laboratório de Fitoquímica e Química Medicinal (LFQM), Departamento de Ciências Exatas, Universidade Federal de Alfenas, 37130-000 Alfenas-MG, Brazil Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610-000 Porto AlegreRS, Brazil Departamento de Farmacologia Básica e Clínica, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, CCS Bloco J Sala J1-029, 21941-902 Rio de Janeiro-RJ, Brazil
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